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Tumor Necrosis Factor-α Promotes Myocarditis in Female Mice Infected with Coxsackievirus B3 Through Upregulation of CD1d on Hematopoietic Cells
Coxsackievirus B3 (CVB3) induces cardiac inflammation (myocarditis) in male but not female C57BL/6 mice. Protection of females correlates with reduced expression of TNF-α and IL-1β at both the mRNA and protein levels in the heart. Treatment of females with 300 ng/mouse of recombinant TNF-α on days +...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Mary Ann Liebert, Inc.
2010
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2883509/ https://ncbi.nlm.nih.gov/pubmed/20121405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vim.2009.0063 |
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