IL-21R Expression on CD8+T Cells Promotes CD8+ T cell Activation in Coxsackievirus B3 Induced Myocarditis

IL-21 is a multi-functional cytokine which can promote survival, proliferation and activation of T and B lymphocytes including CD8 T cells. Previous studies have shown that autoimmune CD8+ T cells are the primary pathogenic effector cell in coxsackievirus B3 (CVB3) induced myocarditis in C57Bl/6 mic...

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Huvudupphovsmän: Liu, Wei, Dienz, Oliver, Roberts, Brian, Moussawi, Mohamad, Rincon, Mercedes, Huber, Sally A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3354021/
https://ncbi.nlm.nih.gov/pubmed/22465422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2012.03.009
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