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Vγ4(+) T Cells Promote Autoimmune CD8(+) Cytolytic T-Lymphocyte Activation in Coxsackievirus B3-Induced Myocarditis in Mice: Role for CD4(+) Th1 Cells

T cells expressing the Vγ4 T-cell receptor (TCR) promote myocarditis in coxsackievirus B3 (CVB3)-infected BALB/c mice. CD1, a major histocompatibility complex (MHC) class I-like molecule, is required for activation of Vγ4(+) cells. Once activated, Vγ4(+) cells initiate myocarditis through gamma inte...

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Bibliografiske detaljer
Main Authors: Huber, S. A., Sartini, D., Exley, M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC136647/
https://ncbi.nlm.nih.gov/pubmed/12368321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.21.10785-10790.2002
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