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Hormonal Regulation of CD4(+) T-Cell Responses in Coxsackievirus B3-Induced Myocarditis in Mice

Coxsackievirus B3 infection causes significant cardiac inflammation in male, but not female, B1.Tg.Eα mice. This gender difference in disease susceptibility correlates with selective induction of CD4(+) Th1 (gamma interferon-positive) cell responses in animals with testosterone, whereas estradiol pr...

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Detalhes bibliográficos
Main Authors: Huber, S. A., Kupperman, J., Newell, M. K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112510/
https://ncbi.nlm.nih.gov/pubmed/10233928
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