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Type III hyperlipoproteinemic phenotype in transgenic mice expressing dysfunctional apolipoprotein E.
Transgenic mice were prepared that expressed a dysfunctional apo E variant, apo E (Arg-112, Cys-142), which is associated with dominant inheritance of type III hyperlipoproteinemia (type III HLP) in humans. Among eight founder mice, plasma apo E (Arg-112, Cys-142) levels varied 100-fold and directly...
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| 出版年: | J Clin Invest |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
1993
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288296/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8376602/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116728 |
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