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Type III hyperlipoproteinemic phenotype in transgenic mice expressing dysfunctional apolipoprotein E.
Transgenic mice were prepared that expressed a dysfunctional apo E variant, apo E (Arg-112, Cys-142), which is associated with dominant inheritance of type III hyperlipoproteinemia (type III HLP) in humans. Among eight founder mice, plasma apo E (Arg-112, Cys-142) levels varied 100-fold and directly...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1993
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC288296/ https://ncbi.nlm.nih.gov/pubmed/8376602 |
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