Type III hyperlipoproteinemic phenotype in transgenic mice expressing dysfunctional apolipoprotein E.

Transgenic mice were prepared that expressed a dysfunctional apo E variant, apo E (Arg-112, Cys-142), which is associated with dominant inheritance of type III hyperlipoproteinemia (type III HLP) in humans. Among eight founder mice, plasma apo E (Arg-112, Cys-142) levels varied 100-fold and directly...

Full description

Saved in:
Bibliographic Details
Main Authors: Fazio, S, Lee, Y L, Ji, Z S, Rall, S C
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC288296/
https://ncbi.nlm.nih.gov/pubmed/8376602
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items