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Differentiation of Kappa Opioid Agonist-Induced Antinociception by Naltrexone Apparent pA(2) Analysis in Rhesus Monkeys,
Naltrexone (NTX) exhibited approximately 3-fold higher affinity for sites labeled by [(3)H]U69,593 (putative κ(1)-selective ligand) than [(3)H]bremazocine (non-selective ligand) in the presence of mu and delta receptor blockade in monkey brain membranes. This led us to test an hypothesis that NTX co...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
1998
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2882849/ https://ncbi.nlm.nih.gov/pubmed/9580592 |
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