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Acetonide Protection of Dopamine for the Synthesis of Highly Pure N-docosahexaenoyldopamine

Direct acetonide protection of the catechol of dopamine has proven to be problematic due to formation of Pictet-Spengler isoquinolines. Here we report an efficient method for acetonide protection of dopamine, allowing preparation of a dopamine prodrug without complications from the Pictet-Spengler r...

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Main Authors: Liu, Zhongqiang, Hu, Bi-Huang, Messersmith, Phillip B.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882309/
https://ncbi.nlm.nih.gov/pubmed/20543896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2010.02.089
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