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Improved method for synthesis of cysteine modified hyaluronic acid for in-situ hydrogel formation

We developed a new strategy for the functionalization of hyaluronic acid by chemical modification of its C-6 hydroxyl groups through an ether bond to obtain a cysteine-hyaluronic acid conjugate. This conjugate is suitable to prepare injectable and in situ formed hydrogels cross-linked by native chem...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Zhang, Xin, Sun, Pengcheng, Huangshan, Lingzi, Hu, Bi-Huang, Messersmith, Phillip B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449282/
https://ncbi.nlm.nih.gov/pubmed/25977950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc02367j
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