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Preclinical Evaluation of the Synthetic Adjuvant SQS-21 and its Constituent Isomeric Saponins

The saponin fraction QS-21 from Quillaja saponaria has been demonstrated to be a potent immunological adjuvant when mixed with keyhole limpet hemocyanin conjugate vaccines, as well as with other classes of subunit antigen vaccines. QS-21 adjuvant is composed of two isomers that include the apiose an...

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Hlavní autoři: Ragupathi, Govind, Damani, Payal, Deng, Kai, Adams, Michelle M., Hang, Jianfeng, George, Constantine, Livingston, Philip O., Gin, David Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882175/
https://ncbi.nlm.nih.gov/pubmed/20450868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.04.034
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