Expression of the phenotypic abnormality of platelet-type von Willebrand disease in a recombinant glycoprotein Ib alpha fragment.

The platelet GP Ib-IX receptor supports platelet adhesion and activation by binding to vWf in the exposed subendothelial matrix. An abnormal GP Ib-IX complex exists in platelet-type or pseudo-von Willebrand disease and has a characteristic increased affinity for soluble vWf resulting in impaired hem...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Murata, M, Russell, S R, Ruggeri, Z M, Ware, J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288214/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8486780/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116438
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