von Willebrand disease type B: a missense mutation selectively abolishes ristocetin-induced von Willebrand factor binding to platelet glycoprotein Ib.

von Willebrand factor (vWF) is a multimeric glycoprotein that mediates the adhesion of platelets to the subendothelium by binding to platelet glycoprotein Ib. For human vWF, this interaction can be induced in vitro by the antibiotic ristocetin or the snake venom protein botrocetin. A missense mutati...

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Detalhes bibliográficos
Main Authors: Rabinowitz, I, Tuley, E A, Mancuso, D J, Randi, A M, Firkin, B G, Howard, M A, Sadler, J E
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC50230/
https://ncbi.nlm.nih.gov/pubmed/1409710
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