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Expression of the phenotypic abnormality of platelet-type von Willebrand disease in a recombinant glycoprotein Ib alpha fragment.

The platelet GP Ib-IX receptor supports platelet adhesion and activation by binding to vWf in the exposed subendothelial matrix. An abnormal GP Ib-IX complex exists in platelet-type or pseudo-von Willebrand disease and has a characteristic increased affinity for soluble vWf resulting in impaired hem...

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Bibliografische gegevens
Hoofdauteurs: Murata, M, Russell, S R, Ruggeri, Z M, Ware, J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1993
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC288214/
https://ncbi.nlm.nih.gov/pubmed/8486780
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