TGF-β regulates the expression of transcription factor KLF6 and its splice variants and promotes co-operative transactivation of common target genes through a Smad3–Sp1–KLF6 interaction

KLF6 (Krüppel-like factor 6) is a transcription factor and tumour suppressor with a growing range of biological activities and transcriptional targets. Among these, KLF6 suppresses growth through transactivation of TGF-β1 (transforming growth factor-β1). KLF6 can be alternatively spliced, generating...

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Main Authors: BOTELLA, Luisa M., SANZ-RODRIGUEZ, Francisco, KOMI, Yusuke, FERNANDEZ-L, Africa, VARELA, Elisa, GARRIDO-MARTIN, Eva M., NARLA, Goutham, FRIEDMAN, Scott L., KOJIMA, Soichi
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882110/
https://ncbi.nlm.nih.gov/pubmed/19076057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20081434
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