Tumor suppressor Activity of KLF6 Mediated by Downregulation of the PTTG1 Oncogene

The tumor suppressor Kruppel-like Factor 6 (KLF6) is frequently inactivated in hepatocellular carcinoma (HCC). To unearth downstream transcriptional targets of KLF6, cDNA microarray analysis of whole liver was compared between KLF6 +/+ and KLF6 +/− mice. Pituitary Tumor Transforming Gene 1 (PTTG1),...

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Main Authors: Lee, Ursula E., Ghiassi-Nejad, Zahra, Paris, Andrew, Yea, Steven, Narla, Goutham, Walsh, Martin, Friedman, Scott L.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827621/
https://ncbi.nlm.nih.gov/pubmed/20116377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.01.049
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