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Reduced Hepatic Stellate Cell Expression of KLF6 Tumor Suppressor Isoforms Amplifies Fibrosis During Acute and Chronic Rodent Liver Injury
Kruppel like factor 6 (KLF6), a zinc finger transcription factor and tumor suppressor, is induced as an immediate-early gene during hepatic stellate cell (HSC) activation. The paradoxical induction of a tumor suppressor in HSCs during proliferation led us to explore the biology of wild type KLF6 (KL...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3522757/ https://ncbi.nlm.nih.gov/pubmed/22961688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26056 |
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