KLF Family Members Regulate Intrinsic Axon Regeneration Ability

Neurons in the central nervous system (CNS) lose their ability to regenerate early in development, but the underlying mechanisms are unknown. By screening genes developmentally regulated in retinal ganglion cells (RGCs), we identified Krüppel-like factor–4 (KLF4) as a transcriptional repressor of ax...

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Autors principals: Moore, Darcie L., Blackmore, Murray G., Hu, Ying, Kaestner, Klaus H., Bixby, John L., Lemmon, Vance P., Goldberg, Jeffrey L.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882032/
https://ncbi.nlm.nih.gov/pubmed/19815778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1175737
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