KLF9 and JNK3 Interact to Suppress Axon Regeneration in the Adult CNS

Neurons in the adult mammalian CNS decrease in intrinsic axon growth capacity during development in concert with changes in Krüppel-like transcription factors (KLFs). KLFs regulate axon growth in CNS neurons including retinal ganglion cells (RGCs). Here, we found that knock-down of KLF9, an axon gro...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Apara, Akintomide, Galvao, Joana, Wang, Yan, Blackmore, Murray, Trillo, Allison, Iwao, Keiichiro, Brown, Dale P., Fernandes, Kimberly A., Huang, Abigail, Nguyen, Tu, Ashouri, Masoumeh, Zhang, Xiong, Shaw, Peter X., Kunzevitzky, Noelia J., Moore, Darcie L., Libby, Richard T., Goldberg, Jeffrey L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2017
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628408/
https://ncbi.nlm.nih.gov/pubmed/28871032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0643-16.2017
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