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KLF Family Members Regulate Intrinsic Axon Regeneration Ability
Neurons in the central nervous system (CNS) lose their ability to regenerate early in development, but the underlying mechanisms are unknown. By screening genes developmentally regulated in retinal ganglion cells (RGCs), we identified Krüppel-like factor–4 (KLF4) as a transcriptional repressor of ax...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2882032/ https://ncbi.nlm.nih.gov/pubmed/19815778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1175737 |
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