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KLF Family Members Regulate Intrinsic Axon Regeneration Ability

Neurons in the central nervous system (CNS) lose their ability to regenerate early in development, but the underlying mechanisms are unknown. By screening genes developmentally regulated in retinal ganglion cells (RGCs), we identified Krüppel-like factor–4 (KLF4) as a transcriptional repressor of ax...

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Sonraí Bibleagrafaíochta
Main Authors: Moore, Darcie L., Blackmore, Murray G., Hu, Ying, Kaestner, Klaus H., Bixby, John L., Lemmon, Vance P., Goldberg, Jeffrey L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882032/
https://ncbi.nlm.nih.gov/pubmed/19815778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1175737
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