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KLF Family Members Regulate Intrinsic Axon Regeneration Ability

Neurons in the central nervous system (CNS) lose their ability to regenerate early in development, but the underlying mechanisms are unknown. By screening genes developmentally regulated in retinal ganglion cells (RGCs), we identified Krüppel-like factor–4 (KLF4) as a transcriptional repressor of ax...

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Main Authors: Moore, Darcie L., Blackmore, Murray G., Hu, Ying, Kaestner, Klaus H., Bixby, John L., Lemmon, Vance P., Goldberg, Jeffrey L.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882032/
https://ncbi.nlm.nih.gov/pubmed/19815778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1175737
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