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New Roles for Cyclin E in Megakaryocytic Polyploidization
Megakaryocytes are platelet precursor cells that undergo endomitosis. During this process, repeated rounds of DNA synthesis are characterized by lack of late anaphase and cytokinesis. Physiologically, the majority of the polyploid megakaryocytes in the bone marrow are cell cycle arrested. As previou...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2881813/ https://ncbi.nlm.nih.gov/pubmed/20392692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.102145 |
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