Cyclophosphamide enhances immunity by modulating the balance of dendritic cell subsets in lymphoid organs

Cyclophosphamide (CTX), a commonly used chemotherapeutic agent can enhance immune responses. The ability of CTX to promote the proliferation of effector T cells and abrogate the function of regulatory T cells (Tregs) has been described. In this study, we examined the effects of CTX treatment on dend...

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Detalles Bibliográficos
Main Authors: Nakahara, Takeshi, Uchi, Hiroshi, Lesokhin, Alexander M., Avogadri, Francesca, Rizzuto, Gabrielle A., Hirschhorn-Cymerman, Daniel, Panageas, Katherine S., Merghoub, Taha, Wolchok, Jedd D., Houghton, Alan N.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2010
Assuntos:
Immunobiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881499/
https://ncbi.nlm.nih.gov/pubmed/20154220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-11-251231
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