Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen.

Autoantibodies reacting with chromatin and its components, histones and DNA, are characteristic of the human autoimmune disease SLE and drug-induced lupus, but the mechanisms of their induction remain unknown. Serial serum samples collected over short intervals from lupus-prone MRL/MP-lpr/lpr and BX...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Burlingame, R W, Rubin, R L, Balderas, R S, Theofilopoulos, A N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288148/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8473512/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116378
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