Immunoglobulin kappa light chain variable region gene complex organization and immunoglobulin genes encoding anti-DNA autoantibodies in lupus mice.

We have investigated the genetic origin of autoantibody production in several strains of mice that spontaneously develop a systemic lupus erythematosus-like disease. Restriction fragment length polymorphism analyses of gene loci encoding kappa light chain variable regions (Igk-V) demonstrated, as sh...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Kofler, R, Strohal, R, Balderas, R S, Johnson, M E, Noonan, D J, Duchosal, M A, Dixon, F J, Theofilopoulos, A N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303593/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3138286/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113689
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