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Immunoglobulin kappa light chain variable region gene complex organization and immunoglobulin genes encoding anti-DNA autoantibodies in lupus mice.

We have investigated the genetic origin of autoantibody production in several strains of mice that spontaneously develop a systemic lupus erythematosus-like disease. Restriction fragment length polymorphism analyses of gene loci encoding kappa light chain variable regions (Igk-V) demonstrated, as sh...

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Detalhes bibliográficos
Main Authors: Kofler, R, Strohal, R, Balderas, R S, Johnson, M E, Noonan, D J, Duchosal, M A, Dixon, F J, Theofilopoulos, A N
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC303593/
https://ncbi.nlm.nih.gov/pubmed/3138286
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