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The role of IFN-gamma in systemic lupus erythematosus: a challenge to the Th1/Th2 paradigm in autoimmunity

The classification of T helper cells into type 1 (Th1) and type 2 (Th2) led to the hypothesis that Th1 cells and their cytokines (interleukin [IL]-2, interferon [IFN]-γ) are involved in cell-mediated autoimmune diseases, and that Th2 cells and their cytokines (IL-4, IL-5, IL-10, IL-13) are involved...

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Autores principales: Theofilopoulos, Argyrios N, Koundouris, Stefanos, Kono, Dwight H, Lawson, Brian R
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC128889/
https://ncbi.nlm.nih.gov/pubmed/11299053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar290
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