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The role of IFN-gamma in systemic lupus erythematosus: a challenge to the Th1/Th2 paradigm in autoimmunity

The classification of T helper cells into type 1 (Th1) and type 2 (Th2) led to the hypothesis that Th1 cells and their cytokines (interleukin [IL]-2, interferon [IFN]-γ) are involved in cell-mediated autoimmune diseases, and that Th2 cells and their cytokines (IL-4, IL-5, IL-10, IL-13) are involved...

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Udgivet i:Arthritis Res
Principais autores: Theofilopoulos, Argyrios N, Koundouris, Stefanos, Kono, Dwight H, Lawson, Brian R
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2001
Fag:
Commentary
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128889/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11299053/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/ar290
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