Dietary fat increases high density lipoprotein (HDL) levels both by increasing the transport rates and decreasing the fractional catabolic rates of HDL cholesterol ester and apolipoprotein (Apo) A-I. Presentation of a new animal model and mechanistic studies in human Apo A-I transgenic and control mice.

Benzer Materyaller

• Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles.
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  Baskı/Yayın Bilgisi: (1992)
• Expression of the human apolipoprotein A-I gene in transgenic mice alters high density lipoprotein (HDL) particle size distribution and diminishes selective uptake of HDL cholesteryl esters.
  Yazar:: Chajek-Shaul, T, ve diğerleri
  Baskı/Yayın Bilgisi: (1991)
• Increased apo A-I and apo A-II fractional catabolic rate in patients with low high density lipoprotein-cholesterol levels with or without hypertriglyceridemia.
  Yazar:: Brinton, E A, ve diğerleri
  Baskı/Yayın Bilgisi: (1991)
• apo B gene knockout in mice results in embryonic lethality in homozygotes and neural tube defects, male infertility, and reduced HDL cholesterol ester and apo A-I transport rates in heterozygotes.
  Yazar:: Huang, L S, ve diğerleri
  Baskı/Yayın Bilgisi: (1995)
• A low-fat diet decreases high density lipoprotein (HDL) cholesterol levels by decreasing HDL apolipoprotein transport rates.
  Yazar:: Brinton, E A, ve diğerleri
  Baskı/Yayın Bilgisi: (1990)