טוען...

apo B gene knockout in mice results in embryonic lethality in homozygotes and neural tube defects, male infertility, and reduced HDL cholesterol ester and apo A-I transport rates in heterozygotes.

apo B is a structural constituent of several classes of lipoprotein particles, including chylomicrons, VLDL, and LDL. To better understand the role of apo B in the body, we have used gene targeting in embryonic stem cells to create a null apo B allele in the mouse. Homozygous apo B deficiency led to...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Huang, L S, Voyiaziakis, E, Markenson, D F, Sokol, K A, Hayek, T, Breslow, J L
פורמט: Artigo
שפה:Inglês
יצא לאור: 1995
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC185864/
https://ncbi.nlm.nih.gov/pubmed/7593600
תגים: הוספת תג
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