apo B gene knockout in mice results in embryonic lethality in homozygotes and neural tube defects, male infertility, and reduced HDL cholesterol ester and apo A-I transport rates in heterozygotes.

Gelijkaardige items

• Knockout of the abetalipoproteinemia gene in mice: Reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes
  door: Raabe, Martin, et al.
  Gepubliceerd in: (1998)
• Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes.
  door: Farese, R V, et al.
  Gepubliceerd in: (1995)
• Longitudinal modeling of frontal cognition in APOE ε4 homozygotes, heterozygotes, and noncarriers
  door: Caselli, R.J., et al.
  Gepubliceerd in: (2011)
• Dietary fat increases high density lipoprotein (HDL) levels both by increasing the transport rates and decreasing the fractional catabolic rates of HDL cholesterol ester and apolipoprotein (Apo) A-I. Presentation of a new animal model and mechanistic studies in human Apo A-I transgenic and control mice.
  door: Hayek, T, et al.
  Gepubliceerd in: (1993)
• SPINK2 deficiency causes infertility by inducing sperm defects in heterozygotes and azoospermia in homozygotes
  door: Kherraf, Zine‐Eddine, et al.
  Gepubliceerd in: (2017)