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Quantifying the distribution of probes between subcellular locations using unsupervised pattern unmixing

Motivation: Proteins exhibit complex subcellular distributions, which may include localizing in more than one organelle and varying in location depending on the cell physiology. Estimating the amount of protein distributed in each subcellular location is essential for quantitative understanding and...

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Detalhes bibliográficos
Main Authors: Coelho, Luis Pedro, Peng, Tao, Murphy, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881404/
https://ncbi.nlm.nih.gov/pubmed/20529939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq220
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