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Robust unmixing of tumor states in array comparative genomic hybridization data

Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness and eventually metastasis. It is hoped that by identifying the common patterns of mutations underlying major cancer sub-types, we can better understand t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tolliver, David, Tsourakakis, Charalampos, Subramanian, Ayshwarya, Shackney, Stanley, Schwartz, Russell
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881397/
https://ncbi.nlm.nih.gov/pubmed/20529894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq213
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