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Robust unmixing of tumor states in array comparative genomic hybridization data

Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness and eventually metastasis. It is hoped that by identifying the common patterns of mutations underlying major cancer sub-types, we can better understand t...

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Библиографические подробности
Главные авторы: Tolliver, David, Tsourakakis, Charalampos, Subramanian, Ayshwarya, Shackney, Stanley, Schwartz, Russell
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881397/
https://ncbi.nlm.nih.gov/pubmed/20529894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq213
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