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Robust unmixing of tumor states in array comparative genomic hybridization data

Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness and eventually metastasis. It is hoped that by identifying the common patterns of mutations underlying major cancer sub-types, we can better understand t...

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Detalhes bibliográficos
Main Authors: Tolliver, David, Tsourakakis, Charalampos, Subramanian, Ayshwarya, Shackney, Stanley, Schwartz, Russell
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881397/
https://ncbi.nlm.nih.gov/pubmed/20529894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq213
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