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Distribution of Fitness Effects Caused by Single-Nucleotide Substitutions in Bacteriophage f1
Empirical knowledge of the fitness effects of mutations is important for understanding many evolutionary processes, yet this knowledge is often hampered by several sources of measurement error and bias. Most of these problems can be solved using site-directed mutagenesis to engineer single mutations...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Genetics Society of America
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2881140/ https://ncbi.nlm.nih.gov/pubmed/20382832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.115162 |
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