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Distribution of Fitness Effects Caused by Single-Nucleotide Substitutions in Bacteriophage f1

Empirical knowledge of the fitness effects of mutations is important for understanding many evolutionary processes, yet this knowledge is often hampered by several sources of measurement error and bias. Most of these problems can be solved using site-directed mutagenesis to engineer single mutations...

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Sonraí Bibleagrafaíochta
Main Authors: Peris, Joan B., Davis, Paulina, Cuevas, José M., Nebot, Miguel R., Sanjuán, Rafael
Formáid: Artigo
Teanga:Inglês
Foilsithe: Genetics Society of America 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881140/
https://ncbi.nlm.nih.gov/pubmed/20382832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.115162
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