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Distribution of Fitness and Virulence Effects Caused by Single-Nucleotide Substitutions in Tobacco Etch Virus

Little is known about the fitness and virulence consequences of single-nucleotide substitutions in RNA viral genomes, and most information comes from the analysis of nonrandom sets of mutations with strong phenotypic effect or which have been assessed in vitro, with their relevance in vivo being unc...

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Bibliographic Details
Main Authors: Carrasco, Purificación, de la Iglesia, Francisca, Elena, Santiago F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169111/
https://ncbi.nlm.nih.gov/pubmed/17898073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00524-07
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