Whole-Genome Profiling of Mutagenesis in Caenorhabditis elegans

Deep sequencing offers an unprecedented view of an organism's genome. We describe the spectrum of mutations induced by three commonly used mutagens: ethyl methanesulfonate (EMS), N-ethyl-N-nitrosourea (ENU), and ultraviolet trimethylpsoralen (UV/TMP) in the nematode Caenorhabditis elegans. Our...

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Autori principali: Flibotte, Stephane, Edgley, Mark L., Chaudhry, Iasha, Taylor, Jon, Neil, Sarah E., Rogula, Aleksandra, Zapf, Rick, Hirst, Martin, Butterfield, Yaron, Jones, Steven J., Marra, Marco A., Barstead, Robert J., Moerman, Donald G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2010
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Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881127/
https://ncbi.nlm.nih.gov/pubmed/20439774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.116616
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