Chromoanasynthetic Genomic Rearrangement Identified in a N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Screen in Caenorhabditis elegans

Chromoanasynthesis is a recently discovered phenomenon in humans with congenital diseases that is characterized by complex genomic rearrangements (CGRs) resulting from aberrant repair of catastrophic chromosomal damage. How these CGRs are induced is not known. Here, we describe the structure and fun...

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Vydáno v:G3 (Bethesda)
Hlavní autoři: Itani, Omar A., Flibotte, Stephane, Dumas, Kathleen J., Moerman, Donald G., Hu, Patrick J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2015
Témata:
Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751554/
https://ncbi.nlm.nih.gov/pubmed/26628482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.024257
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