Chromoanasynthetic Genomic Rearrangement Identified in a N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Screen in Caenorhabditis elegans

Chromoanasynthesis is a recently discovered phenomenon in humans with congenital diseases that is characterized by complex genomic rearrangements (CGRs) resulting from aberrant repair of catastrophic chromosomal damage. How these CGRs are induced is not known. Here, we describe the structure and fun...

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Bibliographische Detailangaben
Veröffentlicht in:G3 (Bethesda)
Hauptverfasser: Itani, Omar A., Flibotte, Stephane, Dumas, Kathleen J., Moerman, Donald G., Hu, Patrick J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2015
Schlagworte:
Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4751554/
https://ncbi.nlm.nih.gov/pubmed/26628482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.024257
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