De Novo Identification of Single Nucleotide Mutations in Caenorhabditis elegans Using Array Comparative Genomic Hybridization

Array comparative genomic hybridization (aCGH) has been used primarily to detect copy-number variants between two genomes. Here we report using aCGH to detect single nucleotide mutations on oligonucleotide microarrays with overlapping 50-mer probes. This technique represents a powerful method for ra...

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Hauptverfasser: Maydan, Jason S., Okada, H. Mark, Flibotte, Stephane, Edgley, Mark L., Moerman, Donald G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666529/
https://ncbi.nlm.nih.gov/pubmed/19189945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.100065
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