Effects of phosphodiesterase 4 inhibition on bleomycin-induced pulmonary fibrosis in mice

BACKGROUND: Pulmonary fibrosis (PF) is a group of devastating and largely irreversible diseases. Phosphodiesterase (PDE) 4 is involved in the processes of remodeling and inflammation, which play key role in tissue fibrosis. The aim of the study was, therefore, to investigate the effect of PDE4 inhib...

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Autori principali: Udalov, Sergey, Dumitrascu, Rio, Pullamsetti, Soni S, Al-tamari, Hamza M, Weissmann, Norbert, Ghofrani, Hossein A, Guenther, Andreas, Voswinckel, Robert, Seeger, Werner, Grimminger, Friedrich, Schermuly, Ralph T
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Research article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881047/
https://ncbi.nlm.nih.gov/pubmed/20444277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2466-10-26
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