Lung vasodilatory response to inhaled iloprost in experimental pulmonary hypertension: amplification by different type phosphodiesterase inhibitors

Inhaled prostanoids and phosphodiesterase (PDE) inhibitors have been suggested for treatment of severe pulmonary hypertension. In catheterized rabbits with acute pulmonary hypertension induced by continuous infusion of the stable thromboxane analogue U46619, we asked whether sildenafil (PDE1/5/6 inh...

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Hlavní autoři: Schermuly, Ralph Theo, Inholte, Christiane, Ghofrani, Hossein Ardeschir, Gall, Henning, Weissmann, Norbert, Weidenbach, Andreas, Seeger, Werner, Grimminger, Friedrich
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2005
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180856/
https://ncbi.nlm.nih.gov/pubmed/16033645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-6-76
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