Lung vasodilatory response to inhaled iloprost in experimental pulmonary hypertension: amplification by different type phosphodiesterase inhibitors

Inhaled prostanoids and phosphodiesterase (PDE) inhibitors have been suggested for treatment of severe pulmonary hypertension. In catheterized rabbits with acute pulmonary hypertension induced by continuous infusion of the stable thromboxane analogue U46619, we asked whether sildenafil (PDE1/5/6 inh...

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Bibliografiske detaljer
Main Authors: Schermuly, Ralph Theo, Inholte, Christiane, Ghofrani, Hossein Ardeschir, Gall, Henning, Weissmann, Norbert, Weidenbach, Andreas, Seeger, Werner, Grimminger, Friedrich
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2005
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180856/
https://ncbi.nlm.nih.gov/pubmed/16033645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-6-76
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