Lung vasodilatory response to inhaled iloprost in experimental pulmonary hypertension: amplification by different type phosphodiesterase inhibitors

Inhaled prostanoids and phosphodiesterase (PDE) inhibitors have been suggested for treatment of severe pulmonary hypertension. In catheterized rabbits with acute pulmonary hypertension induced by continuous infusion of the stable thromboxane analogue U46619, we asked whether sildenafil (PDE1/5/6 inh...

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Bibliographic Details
Main Authors: Schermuly, Ralph Theo, Inholte, Christiane, Ghofrani, Hossein Ardeschir, Gall, Henning, Weissmann, Norbert, Weidenbach, Andreas, Seeger, Werner, Grimminger, Friedrich
Format: Artigo
Language:Inglês
Published: BioMed Central 2005
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180856/
https://ncbi.nlm.nih.gov/pubmed/16033645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-6-76
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