Complete testicular feminization caused by an amino-terminal truncation of the androgen receptor with downstream initiation.

We have characterized the molecular defect causing androgen resistance in two 46,XY siblings with complete testicular feminization. Although binding studies in genital skin fibroblasts showed a reduced Bmax, an increased dissociation rate of ligand, and an 8S peak of dihydrotestosterone binding on s...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Εκδόθηκε σε:	J Clin Invest
Κύριοι συγγραφείς:	Zoppi, S, Wilson, C M, Harbison, M D, Griffin, J E, Wilson, J D, McPhaul, M J, Marcelli, M
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Clinical Investigation 1993
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288066/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8450040/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116269
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