Complete testicular feminization caused by an amino-terminal truncation of the androgen receptor with downstream initiation.

We have characterized the molecular defect causing androgen resistance in two 46,XY siblings with complete testicular feminization. Although binding studies in genital skin fibroblasts showed a reduced Bmax, an increased dissociation rate of ligand, and an 8S peak of dihydrotestosterone binding on s...

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Argitaratua izan da:	J Clin Invest
Egile Nagusiak:	Zoppi, S, Wilson, C M, Harbison, M D, Griffin, J E, Wilson, J D, McPhaul, M J, Marcelli, M
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Clinical Investigation 1993
Gaiak:	Research Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288066/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8450040/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116269
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