Complete testicular feminization caused by an amino-terminal truncation of the androgen receptor with downstream initiation.
We have characterized the molecular defect causing androgen resistance in two 46,XY siblings with complete testicular feminization. Although binding studies in genital skin fibroblasts showed a reduced Bmax, an increased dissociation rate of ligand, and an 8S peak of dihydrotestosterone binding on s...
محفوظ في:
| الحاوية / القاعدة: | J Clin Invest |
|---|---|
| المؤلفون الرئيسيون: | , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Clinical Investigation
1993
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288066/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8450040/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116269 |
| الوسوم: |
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