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Mechanistic Aspects of the Formation of Guanidinohydantoin from Spiroiminodihydantoin under Acidic Conditions
Experimentally, it was observed that the oxidized guanine lesion spiroiminodihydantoin (Sp) contained in highly purified oligodeoxynucleotides slowly converts to guanidinohydantoin (Gh). The reaction is accelerated in the presence of acid. The possible mechanisms of this transformation have been ana...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2880634/ https://ncbi.nlm.nih.gov/pubmed/19146379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx800402y |
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