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Requirement of NOX2 and Reactive Oxygen Species for Efficient RIG-I-Mediated Antiviral Response through Regulation of MAVS Expression

The innate immune response is essential to the host defense against viruses, through restriction of virus replication and coordination of the adaptive immune response. Induction of antiviral genes is a tightly regulated process initiated mainly through sensing of invading virus nucleic acids in the...

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Hoofdauteurs: Soucy-Faulkner, Anton, Mukawera, Espérance, Fink, Karin, Martel, Alexis, Jouan, Loubna, Nzengue, Yves, Lamarre, Daniel, Vande Velde, Christine, Grandvaux, Nathalie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880583/
https://ncbi.nlm.nih.gov/pubmed/20532218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000930
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