Requirement of NOX2 and Reactive Oxygen Species for Efficient RIG-I-Mediated Antiviral Response through Regulation of MAVS Expression

The innate immune response is essential to the host defense against viruses, through restriction of virus replication and coordination of the adaptive immune response. Induction of antiviral genes is a tightly regulated process initiated mainly through sensing of invading virus nucleic acids in the...

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Main Authors: Soucy-Faulkner, Anton, Mukawera, Espérance, Fink, Karin, Martel, Alexis, Jouan, Loubna, Nzengue, Yves, Lamarre, Daniel, Vande Velde, Christine, Grandvaux, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880583/
https://ncbi.nlm.nih.gov/pubmed/20532218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000930
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