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Non-compartment model to compartment model pharmacokinetics transformation meta-analysis – a multivariate nonlinear mixed model

BACKGROUND: To fulfill the model based drug development, the very first step is usually a model establishment from published literatures. Pharmacokinetics model is the central piece of model based drug development. This paper proposed an important approach to transform published non-compartment mode...

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Hlavní autoři: Wang, Zhiping, Kim, Seongho, Quinney, Sara K, Zhou, Jihao, Li, Lang
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880414/
https://ncbi.nlm.nih.gov/pubmed/20522258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-4-S1-S8
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