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Statistical Identifiability and Convergence Evaluation for Nonlinear Pharmacokinetic Models with Particle Swarm Optimization
The statistical identifiability of nonlinear pharmacokinetic (PK) models with the Michaelis-Menten (MM) kinetic equation is considered using a global optimization approach, which is particle swarm optimization (PSO). If a model is statistically non-identifiable, the conventional derivative-based est...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3906649/ https://ncbi.nlm.nih.gov/pubmed/24216078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmpb.2013.10.003 |
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