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A Novel Gibbs Maximum A Posteriori (GMAP) Approach on Bayesian Nonlinear Mixed-Effects Population Pharmacokinetics (PK) Models

In this paper, various Bayesian Monte Carlo Markov Chain (MCMC) methods and the proposed algorithm, Gibbs maximum a posteriori (GMAP) algorithm, are compared for implementing the nonlinear mixed-effects model in pharmacokinetics (PK) studies. An intravenous two-compartmental PK model is adopted to f...

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Bibliografische gegevens
Hoofdauteurs: Kim, Seongho, Hall, Stephen D., Li, Lang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829744/
https://ncbi.nlm.nih.gov/pubmed/20183435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543400902964159
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